American science documentary television series that premiered on March 9, 2020, on National Geographic. The series is a follow-up to the 2014 television series Cosmos: A Spacetime Odyssey, which followed the original Cosmos: A Personal Voyage series presented by Carl Sagan on PBS in 1980. The series is presented by astrophysicist Neil deGrasse Tyson, written, directed, and executive-produced by Ann Druyan and Brannon Braga, with other executive producers being Seth MacFarlane and Jason Clark. The series consists of 13 episodes that were broadcast over seven weeks. The series had its broadcast television premiere on Fox on September 22, 2020. Braga explains that "Possible Worlds refers to planets far, far away, but also ... the future as a possible world."

Juan de los Santos, a former undercover cop from Paraguay, once ready to take down the biggest drug cartel in Latin America, has lost everything; his wife and kids brutally murdered on a cold dark night and with them, his will to live. Juan, himself didn't survive unscathed; on that cold night he took two bullets, one still in his heart, the other one damaging a part of his brain, cursing him sporadic amnesia. In an internal and external struggle with his own demons, Juan must defeat incredible odds to save innocent people. Sleepless, and afflicted by treacherous nightmares of that night, he is willing to take any job to alleviate his suffering.