When Ji-won, a 37-year-old cancer patient, walks in on her husband and best friend, she realizes her whole life has been a lie. What’s worse, she dies a tragic death at the hands of her husband. Would things have been different if she had made different choices? Fortunately for Ji-won, she is given the chance to rewrite her fate when she is reincarnated as her younger self. This time, she vows to live a happy life. But first comes revenge. Her plan? To marry off her now former best friend to her lying, cheating husband.

Based on the Danggun myth that bears become humans after eating garlic and mugwort, it depicts the story of twin Asiatic Bear brothers, who were managed by the Pro-North Korean Institute of Technology, disappearing one day after eating mugwort and garlic.

Choi Ban Do and Ma Jin Joo are both 38-years-old and a married couple. Choi Ban Do has been burdened with being the breadwinner and Ma Jin Joo is a housewife with low self-esteem. Even though they loved each other when they married, they now hate each other. They both regret marrying at such a young age. The couple travel through time and find themselves as 20-year-old university students, when they met for the first time.

During the Joseon Dynasty, the Secret Royal Inspectors are the eyes and ears of the king. They travel the provinces undercover and listen to the plight of the common people, investigating abuses and corruption of government officials.

Jun is a top agent of the National Intelligence Service who can strike down dozens of terrorists in one fell swoop. Disenchanted with his life, Jun disguises his death and succeeds in leaving the NIS to lead a normal life as a family man and fulfill his dream of becoming a webtoon artist. However, his unexciting webtoons are ignored by readers and even his wife. Depressed and angry at himself, Jun suddenly draws a webtoon of his past as a secret agent.

Baek Beom has worked as a forensic doctor for 10 years. He has a bad personality, but he is excellent with his work. Baek Beom does not open his mind to other people. Eun Sol is a rookie prosecutor with a warm heart. She has a bright personality and she comes from wealth family background. The forensic doctor and prosecutor work together to solve cases.

Kang Dong-Goo dreams of becoming a movie director, but he is cynical due to bad luck. Cheon Joon-Ki wanted to follow in his father's footsteps and become an actor, but he is now just a minor actor. Bong-Doo-Sik came to Seoul to become a scenario writer, but things have not been easy for him. These 3 men run the guest house Waikiki in Itaewon, South Korea. Their guest house is facing bankruptcy and then a mysterious baby and single mother appear at Waikiki.

Seo-Ri's mother Queen Sim was unable to have a child. She went to a shaman to help her have a child. With the help of shaman Hong-Joo's black magic, Queen Sim was able to have a boy and girl twins. The girl, Seo-Ri, was put under a curse and abandoned deep in the mountains. She meets Heo Jun, a young man, there.

On the eve of the founding of the Joseon Dynasty, a whale swallows the Emperor's Seal of State being brought to Joseon by envoys from China. With a big reward on whoever brings back the royal seal, mountain bandits led by Jang Sa-jung go out to sea to hunt down the whale. But he soon clashes with Yeo-wol, a female captain of pirates, and unexpected adventure unfolds.